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Oxygen Club of California World Congress 2012
June 20–23
Alba, Italy
Speakers and Topics
Keynote Lectures
Richard Weindruch |
Metabolic reprogramming, caloric restriction, and aging |
I – NRF2-Driven Regulation of Antioxidant Defenses
Masayuki Yamamoto |
Molecular mechanisms of Keap1-Nrf2 pathway in stress response and cancer evolution |
Thomas Kensler |
Keap1-Nrf2 signaling: targets for disease prevention
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Giovanni Mann |
Nrf2-mediated redox signaling in endothelial cells: consequences for cardiovascular disease |
Young-Joon Surh |
Adaptive survival response mediated by the Nrf2-induced HO1 upregulation |
Regina Brigelius-Flohé |
Nrf2 target genes are induced under marginal selenium deficiency |
II – Nutrient-Gene Interactions and Epigenetics
Ben van Ommen |
Micronutrient genomics: an overview |
Steven Zeisel |
Functional genetic polymorphisms in genes of choline metabolism |
Frederick E. Domann |
The redox basis of epigenetic control |
Emily Ho |
Dietary histone deacetylase inhibitors for cancer prevention |
Bharat B. Aggarwal |
Epigenetic changes induced by curcumin |
Irfan Rahman |
Redox epigenetic modifications by dietary bioactive compounds in inflammation |
III – Novel Roles of Micronutrients
Vittorio Calabrese |
Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of hormesis and vitagens |
Patricia Oteiza |
Zinc and redox signaling in the developing brain |
Helen McNulty |
MTHFR genotype and riboflavin: a novel gene-nutrient interaction affecting blood pressure |
David Heber |
Biomedical action of pomegranate ellagitannins |
Louis Casteilla |
Redox metabolism, coenzyme Q, and obesity |
David Carlson |
Redox modulation of cell signaling by lipoic acid |
Andrew Levy |
Pharmacogenomic interactions between vitamin E and the haptoglobin genotype in the prevention of diabetic vascular disease |
IV – Lipid Oxidation and Signaling
Etsuo Niki |
Physiological and unregulated membrane lipid oxidation |
Laszlo Nagy |
Transcriptional interactions involving hormone nuclear receptors shaping macrophage polarity and activity |
Gabriella Leonarduzzi |
Lipid oxidation-mediated mechanisms of destabilization of the atherosclerotic plaque |
Luigi Iuliano |
Oxysterols in the pathogenesis of inflammatory-based disease |
Francisco Schopfer |
Electrophilic nitro-fatty acids as anti-inflammatory mediators in the vascular compartment |
Oren Tirosh |
High cholesterol diet-induced impairment of glucose homeostasis in mice with fatty liver: role of inducible NOS |
Gaetano Serviddio |
Non-alcoholic fatty liver disease, oxidative stress, and mitochondria |
Corinne M. Spickett |
Lipid-protein adducts as biomarkers of inflammatory-based diseases in humans |
Tilman Grune |
Protein oxidation: reducing the toxic effects |
V – Epigenetics, Metabolism, and Aging
Mario Fraga |
Epigenetic regulation of aging |
Gregory Brewer |
Epigenetic redox shift, nutrients, aging, and insulin |
Silvia Gravina |
Role of random changes to epigenetic marks in aging |
Gayathri Swaminathan |
Relocation of mtDNA to nucleus: implications for mitochondrial mutations |
José Viña |
Modulation of aging genes: importance in longevity and age-associated frailty |
Matthew O'Connor |
Relocation of mtDNA to the nucleus: implication for mitochondrial mutations |
Suresh Rattan |
Molecular gerontology: from molecules to hormesis |
Kelvin J. A. Davies |
Proteolytic signaling dysfunction in aging |
Malcolm Jackson |
Reactive oxygen species in muscle wasting during aging |
Leo Rodriguez-Mañas |
Frailty: a basic and clinical challenge for the future |
Maria Cristina Polidori |
Oxidative stress and the link of pathophysiology of Alzheimer's disease with vascular pathology |
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